Adulterated Effects of Nitric Oxide–Generating Donors
نویسندگان
چکیده
منابع مشابه
Nitric oxide donors: novel cancer therapeutics (review).
The development of cancer cell resistance to various cytotoxic stimuli continues to be a major challenge in oncology and novel therapeutic approaches are urgently needed. Nitric oxide (NO) is emerging as a potential anti-oncogenic agent to overcome tumor cell resistance to conventional therapeutic agents. NO is a ubiquitous, water-soluble, free radical gas that exerts a wide range of biological...
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Deaii Sir,?"With reference to a correspondence which appeared in the Mirror of 12th instant, from Bhobun IVIohun Sircar, drawing attention to an article in the August number of the Indian Medical Gazette on the adulteration of quinine, I beg to offer a few remarks on the subject, and to ask your opinion if it is the duty of the Health Officer to suppress those frauds which are committed by the ...
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Introduction: Diabetic foot ulcer is a serious complication of diabetes mellitus; it consists of lesions in the deep tissues associated with neurological disorders and peripheral vascular disease in the lower limbs. Delayed wound healing in diabetes leads to long-term hospitalization and even amputation of distal organs. Diabetes mellitus is associated with decreased nitric oxide bioavailabilit...
متن کاملEffects of nitric oxide donors on non-pregnant and pregnant rat uterine and aortic smooth muscle.
OBJECTIVE To compare the effects of nitric oxide (NO) donors, diethylamine/nitric oxide (DEA/NO) and nitroglycerin (NTG), on isolated uterine and aortic tissues from non-pregnant, mid and late pregnant rats. METHODS The uterus and thoracic aorta were obtained from non-pregnant (estrous cycle) and pregnant Sprague-Dawley rats on day 14 and day 21. The uterine and aortic rings were incubated in...
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Nitric oxide (NO) is produced continuously from the endothelium and plays a pivotal role in the control of vascular tone. Many of the current therapeutic agents that increase blood flow through production of NO have to be taken orally and can produce significant adverse side effects. We now report on some novel NO-donor drugs, based on thiosugars that generate NO spontaneously. From the range o...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2008
ISSN: 0022-202X
DOI: 10.1038/sj.jid.5701162